A biography of physicist Sir Isaac Newton, who invented calculus, discovered a law of gravity, and made other significant scientific discoveries in the seventeenth and eighteenth centuries.

After the mysterious drowning of his mother Elizabeth Vogelsang, who was writing a controversial biography of Isacc Newton, Cameron Brown recruits his former lover to complete the book. This plunges her to into probing two series of murders, the 17th century murders of several who stood between Newton and his studies and present day targets of those who offend the an animal rights group.