Zane belongs to a world in which the scientific revolution has been followed by the revolution of magic, and he is thrust into the role of Death.

While working at pleasant but mundane summer jobs in San Francisco, fifteen-year-old twins, Sophie and Josh, suddenly find themselves caught up in the deadly, centuries-old struggle between rival alchemists, Nicholas Flamel and John Dee, over the possession of an ancient and powerful book holding the secret formulas for alchemy and everlasting life.

Since the car accident that claimed the lives of her family, sixteen-year-old Ever can see auras and hear people's thoughts, and she goes out of her way to hide from other people until she meets Damen, another psychic teenager who is hiding even more mysteries.